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Description

Ca 2+ is not metabolized and an overload of mitochondrial Ca 2+ may break down the electrochemical proton gradient resulting in a deficit of ATP followed by necrosis [89]

Pharmacol Rep 2013, 65 (1), 179186

In groups supplemented with vitamin E, levels of oxidative stress markers were decreased, and a reduction in vitamin E concentration contributed to the progressing of AD in dogs (164)